D50X Summit
October 20, 2022

D50X Summit

The Next Decade of Disruption

What areas and sectors are ripe for disruption? Which technologies and innovations will power the next upheaval in the business world? Powered by 10 years of CNBC’s groundbreaking Disruptor 50 list, and featuring intelligence and input from a who’s who from our past and present D50 companies, we’ll look what will be the trends that disrupt, enable and power growth and produce amazing returns for the next ten years and beyond.


Stéphane Bancel

Stéphane Bancel has served as Moderna's Chief Executive Officer since October 2011 and as a member of Moderna’s board of directors since March 2011. Before joining the company, Mr. Bancel served for five years as Chief Executive Officer of the French diagnostics company bioMérieux SA. From July 2000 to March 2006, he served in various roles at Eli Lilly and Company, including as Managing Director, Belgium and as Executive Director, Global Manufacturing Strategy and Supply Chain. Prior to Lilly, Mr. Bancel served as Asia-Pacific Sales and Marketing Director for bioMérieux.

Mr. Bancel currently serves on the board of directors of Indigo. He is currently a Venture Partner at Flagship Pioneering. Mr. Bancel holds a Master of Engineering degree from École Centrale Paris (ECP), a Master of Science in chemical engineering from the University of Minnesota, and an M.B.A. from Harvard Business School.

Jenny Just

Jenny Just co-founded PEAK6 in 1997 with $1.5M in seed capital as a proprietary options trading firm. Since then, she has grown it into a multibillion-dollar financial services and technology giant housing the next generation of products and service brands including PEAK6 Capital Management, PEAK6 Strategic Capital, Apex Fintech Solutions, Apex Crypto, PEAK6 InsurTech, Evil Geniuses, and Zogo. Jenny and her co-founder have created or turned around more than 15 operating companies and made 100s of private investments.

Jenny is passionate about finding opportunities for women to succeed at every table. This passion led her to launch Poker Power in 2020, a woman-led company that teaches poker to all who identify as female and by extension, teaches women strategic thinking, capital allocation, and decision-making skills. Additionally, Jenny has created programs to help women and underrepresented professionals advance their careers including the Women’s Trading Experience, Women’s Technology Experience and Fintech In Action.

Jay Parikh

Jay Parikh is the Co-CEO of Lacework where he leads its innovation engine – including its product, engineering, and infrastructure efforts. In 2013, Jay also joined the Board of Directors at leading enterprise software company Atlassian. Prior to Lacework, Jay served as vice president of infrastructure engineering at Facebook, where he led the engineering and operations teams responsible for building and maintaining the company’s infrastructure that serves more than one billion users, developers, and partners worldwide. Parikh also served as vice president of engineering at Akamai Technologies, where he helped build the world’s largest and most globally distributed computing platform and where he linked up with the other Lacework Co-CEO, David Hatfield. Parikh is a member of the Advisory Council of Big Data Fund 2 and the Board of Advisors of Ooyala, Inc. He also serves as an advisor of Revinate, Inc., and is a technology advisor to several early-stage companies. He has filed several U.S. patents. Parikh holds a bachelor’s degree from Virginia Tech University.

Ryan Petersen

Ryan Petersen is the Founder and Co-CEO of Flexport. Prior to starting Flexport to fix the user experience in global trade, Ryan was co-founder and CEO of ImportGenius.com, a data-as-a-service business for global shipping. He holds a degree in economics from the University of California, Berkeley and an MBA from Columbia University.

Robert F. Smith

Robert F. Smith is the Founder, Chairman and CEO of Vista Equity Partners. He directs Vista’s investment strategy and decisions, firm governance and investor relations. Vista currently manages equity capital commitments of over $100Bn and oversees a portfolio of over 80 software companies that employ over 100,000 people worldwide. Since Vista’s founding in 2000, Smith has overseen over 590 completed transactions by the firm representing more than $290 billion in aggregate transaction value.

In 2020, Smith was named as one of the TIME 100 Most Influential People in the World. In 2017, Smith was named by Forbes as one of the 100 Greatest Living Business Minds. Robert has also been named Cornell Entrepreneur of the Year.

Born in Colorado to two parents with EdDs, Smith trained as an engineer at Cornell University, earning his B.S. in Chemical Engineering. Following his MBA from Columbia Business School with honors, Smith worked at Kraft General Foods, where he earned two United States and two European patents. In 1994, he joined Goldman Sachs in tech investment banking, first in New York and then in Silicon Valley.

Smith is the founding director and President of the Fund II Foundation, which is dedicated to preserving the African American experience, safeguarding human rights, providing music education, preserving the environment while promoting the benefits of the outdoors, and sustaining critical American values. In January 2016, Cornell University honored Mr. Smith’s leadership by naming the Robert Frederick Smith School of Chemical and Biomolecular Engineering.

In 2017, Smith signed on to the Giving Pledge. His gift of $20 million was the largest by an individual donor at the time to the National Museum of African American History and Culture.

Smith is the Chairman of Carnegie Hall. He serves on the Board of Directors for the Business Roundtable, the Board of Overseers of Columbia Business School, as a Member of the Cornell Engineering College Council, and is a Trustee of the Boys and Girls Clubs of San Francisco.

Smith has been a leading voice advocating for companies to take diverse internship candidates in STEM fields. Under his leadership, in 2019, Fund II Foundation launched internXL, a platform to match leading companies with diverse internship candidates.

In 2019, Smith received an honorary doctorate from Morehouse College and made headlines by announcing that he would cover the student loans of nearly 400 Morehouse College 2019 graduates in a commencement address. After his Morehouse pledge, Smith founded the Student Freedom Initiative to relieve the crushing burden of student debt for STEM students at all HBCUs.

He also co-leads the Southern Communities Initiative, a catalytic program for racial equity across six southern communities representing half of the Black population in the U.S.

Ivan Soto-Wright

Ivan Soto-Wright is the Co-founder & CEO of MoonPay, the leading crypto payments and Web 3 infrastructure provider. Moonpay recently raised $555 million in their Series A round from top venture capitalists, influential figures and organizations from the worlds of music, sports, media & entertainment.

A noted investor, and early adopter of digital assets, Ivan Soto-Wright is known as a top incubator and entrepreneur in the fintech space. Ivan Soto-Wright is the Founder & General Partner of HODL.vc., and was previously Co-Founder and CEO of Saveable, an automated savings fintech business. Ivan graduated from the George Washington University with Special Honors in Economics, and studied Philosophy, Politics and Economics at The University of Oxford.

Anne Wojcicki

Anne co-founded 23andMe in 2006, three years after the first human genome was sequenced. Her goal was audacious: to help people access, understand, and benefit from the human genome and fundamentally change healthcare in the process. Prior to founding 23andMe, Anne spent a decade on Wall Street investing in healthcare and felt frustrated by a system built around monetizing illness instead of incentivizing prevention. She wanted to flip that model on its head and build a business that helps people prevent illness rather than profit from it. Anne focused on empowering people with direct access to genetic information so that they could use their data to make decisions that could lower their risks for disease. Under her leadership, 23andMe now provides the only personal genetic test with FDA authorization to deliver health information directly to consumers.

A pioneer in the direct-to-consumer DNA testing space, Anne’s vision and persistence have not only allowed 23andMe to provide millions with access to genetic information, but have powered an industry-first crowdsourcing approach to genetic research and drug development – yielding more than 200 scientific publications and two therapeutic programs in phase 1 clinical trials.

Anne graduated from Yale University with a BS in Biology.

Vikas Agarwal

Vikas is a Principal within PwC’s Cyber, Risk, and Regulatory platform and currently serves as the leader for Risk Products Technology and the Financial Crime Unit. In his role within Risk Products, Vikas helps run and incubate from ideation to go-to-market, and delivers a $300M software-as-a-service business focused on transforming professional services to a more digital approach in serving clients faster and with more value. Within Financial Crimes he focuses on helping clients deal with matters related to money laundering, fraud, sanctions, and trade surveillance.

His deep industry insights on the business, technology, data, and regulatory dimensions of financial services assist clients in reducing costs through using sustainable analytics solutions that allow for better testing, insights, monitoring, and metrics-based indicators that reduce risk. Vikas has experience in leading many organizations design, strategy and remediation efforts at large global financial institutions, fintech and payments companies and regional US banks.

Vikas holds a B.S in Finance from Case Western Reserve University in Cleveland, OH. He is a Certified Regulatory Professional as awarded by the Wharton School of Business, FINRA institute and received his M.B.A. from Columbia University.

Catherine Buan

Catherine leads Investor Relations, Sustainability and ESG Reporting at Asana. Her role at Asana punctuates the developing landscape of Finance and ESG. Measuring and reporting progress in ESG will drive measurable outcomes and provide transparency to all stakeholders, from customers to employees to investors. This promotes trust, supports long term business growth and can elevate a company's valuation.

Having started her career in investment banking, she has spent over 25 years helping companies maximize valuation during critical junctures, including acquisitions, turnarounds and IPO’s. She’s widely known across tech investing for her role in launching high profile IPO’s including Asana, Lyft, Docusign, Okta, AppDynamics, Ariba and many others. At Asana, she works to elevate their market valuation by enhancing their brand around trust, mitigating perceived risks and helping to drive revenue, with a proactive, transparent and comprehensive ESG strategy.

Catherine has long been involved in leading Economic Development organizations such as Philippine Development Foundation, where she served as President, and other humanitarian aid efforts such as the American Red Cross. She earned a BA in Economics from Stanford University.

Larry Lawrence

Larry Lawrence is Head of Sustainable Finance Data for the U.S. market at ICE.

In this role, Larry is responsible for developing and delivering ICE’s data strategy and product roadmap surrounding sustainable finance. He works with financial market participants to support their and their clients’ sustainable finance goals in areas such as ESG.

He was previously head of ESG and climate product strategy for the wealth management, private assets, fund ratings, ESG reporting product lines at MSCI. He joined MSCI from KLD, a pioneer in the field of ESG investing. Larry served as a product manager with KLD, RiskMetrics and later MSCI, where he was instrumental in the development of the firm’s ESG ratings, governance metrics and ESG controversies product lines, as well as MSCI’s ESG platforms.

Larry holds a bachelor’s degree in computer science from Newbury College.

Lynn Martin

Lynn Martin is President of NYSE Group, which includes the New York Stock Exchange, the world’s largest stock market.

Martin is the 68th President of the New York Stock Exchange and the second woman to lead the exchange in its 229-year history. The NYSE, the premier venue for capital raising, is the listing home to 2,400 of the world’s most influential and innovative companies.
In addition to the exchange, NYSE Group includes four fully electronic equity markets, including NYSE Arca, the industry leader in ETFs, and two options exchanges.

Martin is also Chair of Fixed Income & Data Services at Intercontinental Exchange, Inc. (NYSE: ICE), the parent of NYSE Group. Most recently, she was President of that business, responsible for ICE Bonds execution venues, securities pricing and analytics, reference data, indices, desktop solutions, consolidated feeds and connectivity services that cover all major asset classes.

She previously served as President of ICE Data Services, COO of ICE Clear U.S., and in a number of leadership roles including CEO of NYSE Liffe U.S. and CEO of New York Portfolio Clearing. Martin began her career at IBM in its Global Services organization.

Martin holds a BS in Computer Science from Manhattan College and an MA in Statistics from Columbia University. She serves on the Manhattan College Board of Trustees as well as the Advisory Board of the School of Science and is a member of the Phi Beta Kappa National Honor Society.

Jen Rogers

Jen Rogers is an award-winning financial reporter and anchor. Most recently, she was the host of The Final Round, Yahoo! Finance’s live daily close-of-market show and Time for Change, its program focused on issues of diversity and social justice in the business world.

Before joining Yahoo! Finance, Jen spent more than a decade in television -- at CNN, MSNBC, and Reuters. She has had a front row seat for the biggest tech and finance stories of our time and has interviewed a who’s who of business leaders, including Warren Buffett and Elon Musk.

Jen is a runner, a reader, and a cancer survivor. She co-founded Comedy vs Cancer, an annual event which raises money for cancer research at Memorial Sloan Kettering Cancer Center, where she also serves on the Patient and Family Advisory Council.

Caroline Woods

NYC-based video presenter and producer with extensive experience in all areas of television and digital video development and production, including anchoring, reporting, writing, producing, interviewing, editing, social media, hiring and team development. Organized, detail-oriented and collaborative leader with comprehensive experience in business news, media training and startups.

Julia Boorstin

Julia Boorstin is CNBC’s Senior Media & Tech Correspondent based at the network’s Los Angeles Bureau. She covers media with a special focus on the intersection of media and technology. Boorstin also plays a key role on CNBC’s bi-coastal tech-focused program “TechCheck” (M-F, 11AM-12PM ET/8AM-9AM PT) delivering reporting, analysis and interviews around streaming, social and the convergence of media and technology. She joined CNBC in May 2006 as a general assignment reporter and in 2007 moved to Los Angeles to cover media.

In 2013, Boorstin created and launched the CNBC Disruptor 50, an annual list she oversees, highlighting the private companies transforming the economy and challenging companies in established industries. Additionally, she reported a documentary on the future of television for the network, “Stay Tuned…The Future of TV.” She also helped launch CNBC’s ‘Closing the Gap’ initiative covering the people and companies closing gender gaps, and leads CNBC’s coverage of studies on this topic. She is currently writing a book called, “WHEN WOMEN LEAD: What they achieve, Why they succeed, and How we can learn from them,” about female founders that Simon & Schuster’s Avid Reader imprint is publishing in October 2022.

Boorstin joined CNBC from Fortune magazine where she was a business writer and reporter since 2000. During that time, she was also a contributor to “Street Life,” a live market wrap-up segment on CNN Headline News.

In 2003, 2004 and 2006, The Journalist and Financial Reporting newsletter named Boorstin to the “TJFR 30 under 30” list of the most promising business journalists under 30 years old. She has also worked for the State Department’s delegation to the Organisation for Economic Co-operation and Development and for Vice President Gore’s domestic policy office.

She graduated with honors from Princeton University with a B.A. in history. She was also an editor of The Daily Princetonian.

Frank Holland

Frank Holland is anchor of CNBC’s “Worldwide Exchange” (M-F, 5AM-6AM ET), which broadcasts from CNBC Global Headquarters in Englewood Cliffs, N.J.

He is also a Transports & Tech Correspondent for the network. Holland focuses on reporting and executive interviews for cloud computing, enterprise software and cybersecurity companies in the technology sector as well as trucking, e-commerce and shipping companies in the supply chain sector. Previously, he was a general assignment reporter for CNBC starting in September 2018.

During his time at the network, Holland has covered a wide range of national stories including: the first shipments of the COVID-19 vaccine, the death of George Floyd, Hurricane Ida and the first Kentucky Derby after the pandemic.

Holland also covers Diversity, Equity and Inclusion under CNBC’s Equity and Opportunity brand including the 100th Anniversary of Black Wall Street, diversity in tech and various network specials.

Before joining CNBC, Holland was an anchor and reporter at NBC Boston and WCVB in Boston covering national stories and major local news including the famous “28-3” Patriots Super Bowl victory, The “Texting-Suicide” trial and the Boston Marathon. Holland also enterprise original series and hosted live events, including “Black in Boston”, a weekly business segment and the NBC Education Town Hall in Boston.

Prior to Boston, Holland spent three years as an anchor/reporter at WGN-TV in Chicago, where he covered the presidential inauguration of Barack Obama, the Republican and Democratic national conventions, as well as the National College Football Championship. He also held positions at NBC Affiliate WDIV in Detroit, News 12 in New York, and spent several years in television news in both the Virgin Islands and Alaska.

Holland holds a Master’s Degree in Business Administration from Bentley University and a Bachelor of Arts in Political Science from the University of Pittsburgh. He is a proud member of Kappa Alpha Psi Fraternity, Inc., the Urban League and the National Association of Black Journalists.

Joe Kernen

Joe Kernen is co-anchor of "Squawk Box" (M-F, 6AM-9AM ET), CNBC's signature morning program. It is a fast-paced, irreverent look at the world of Wall Street, and the longest running show on the network. Kernen is based in CNBC's global headquarters in Englewood Cliffs, N.J.

Prior to his anchoring duties, Kernen was CNBC's On-Air Stock Editor and was featured throughout the business day on CNBC.

Kernen came to CNBC in the 1991 merger with Financial News Network, having joined FNN after a 10-year career as a stockbroker. After training at Merrill Lynch, he rose to the level of vice-president at both EF Hutton and Smith Barney. Focusing on small-to-medium-sized corporations, he managed corporate cash accounts and qualified retirement plans in addition to key employees' personal assets.

Kernen holds a bachelor's degree from the University of Colorado in molecular, cellular and developmental biology as well as a master's degree from Massachusetts Institute of Technology. During his graduate studies, he worked at the MIT Center for Cancer Research, one of the world's premier institutions. His work focused on mouse erythroleukemia cells and resulted in a series of publications in well-known scientific journals including CELL, Developmental Biology and Cold Spring Harbor Symposia on Quantitative Biology.

Riley de León

Riley de León is a Producer for CNBC. He graduated from the University of Missouri with a bachelor’s degree in journalism and an emphasis in strategic communications and entrepreneurship.

Tyler Mathisen

Tyler Mathisen co-anchors CNBC's "Power Lunch" (M-F, 1PM-3PM ET), one of the network's longest running program franchises. He is also Vice President, Events Strategy for CNBC, working closely with the network's events team to grow the rapidly expanding business.

Previously, Mathisen was co-anchor of "Nightly Business Report," an award-winning evening business news program produced by CNBC for U.S. public television. In 2014, NBR was named best radio/TV show by the Society of American Business Editors and Writers (SABEW). Since joining CNBC in 1997, Mathisen has held a number of positions including managing editor of CNBC Business News, responsible for directing the network's daily content and coverage. He was also co-anchor of CNBC's "Closing Bell."

Mathisen has reported one-hour documentaries for the network including "Best Buy: The Big Box Fights Back," "Supermarkets Inc: Inside a $500 Billion Money Machine" and "Death: It's a Living." Mathisen was also host of the CNBC series "How I Made My Millions."

Prior to CNBC, Mathisen spent 15 years as a writer, senior editor and top editor for Money magazine. Among other duties, he supervised the magazine's mutual funds coverage, its annual investment forecast issue and its expansion into electronic journalism, for which it won the first-ever National Magazine Award for New Media in 1997.

In 1993, Mathisen won the American University-Investment Company Institute Award for Personal Finance Journalism for a televised series on "Caring for Aging Parents," which aired on ABC's "Good Morning America." Mathisen served as money editor of "GMA" from 1991 to 1997. He also won an Emmy Award for a report on the 1987 stock market crash that aired on New York's WCBS-TV.

A native of Arlington,Va., Mathisen graduated with distinction from the University of Virginia.


The Unlikeliest Household Name

The power of messenger RNA is obvious now, the basis of the Covid vaccines that blunted the force of the pandemic. It wasn’t so obvious in 2015, when Moderna topped CNBC’s annual Disruptor 50 list. The CEO joins us to discuss what became one of the greatest medical races in history and what lies ahead for a now decade-old company that’s fighting to protect its patented technology. 

Stéphane Bancel, Moderna CEO
Interviewer: Joe Kernen, “Squawk Box” Co-Anchor

Watch the full interview

Land, Air and Sea: Disruptive Innovation and the Supply Chain

Last year, as the supply chain crisis persisted, Flexport had its own bottleneck: a waiting list. Freight is a trillion-dollar industry that’s failed to move with the speed of the 21st century, so it’s no surprise that the company topped this year’s CNBC Disruptor 50 list. Founder and CEO Ryan Petersen joins us to discuss how a once well-tuned machine has become a disaster that’s fueling some of the worst inflation in decades, as well as the technology capable of bringing things back under control. 

Ryan Petersen, Flexport Founder & CEO
Interviewer: Julia Boorstin, CNBC Senior Media & Tech Correspondent

Watch the full interview

The Future of Disruption Must be More Diverse

By now, the case for investing in more women and minority-led startups has been well established, but progress remains slow. And in 2022, rising interest rates and recession fears have actually caused a slowdown in venture funding of diverse-led firms, reversing the incremental progress that was starting to be made. CNBC’s Frank Holland leads this important conversation with legendary venture and private equity investor Robert Smith on how to create opportunity for more diverse-led disruptive companies to be formed, financed, counseled and led, regardless and even because of the current state of the economy.

Robert F. Smith, Vista Equity Partners Founder, Chairman and CEO
Interviewer: Frank Holland, CNBC General Assignment Reporter

Watch the full interview

Breakout Session

Disruption in Action: Web3 & Cybersecurity 

Crypto enthusiasts say their vision for the web would decentralize it, pushing it closer to its roots. But doing so presents novel security threats we’ve only just begun to confront with the internet in its current form. In this panel, the CEOs of MoonPay and Lacework, both first-time CNBC Disruptor 50 companies, join us to discuss the emerging threats out there and the best ways to protect everyone from token holders to NFT creators and more. 

Ivan Soto-Wright, MoonPay Co-Founder & CEO
Jay Parikh, Lacework Co-CEO & Former Facebook VP of Engineering
Moderator: Riley de León, CNBC Producer
Watch the full session

Crafting an ESG Narrative
Sponsored and programmed by NYSE

Are you ready for the public markets? Investors increasingly consider ESG when they analyze a company’s prospects. Companies entering the public markets are taking the opportunity to craft their message and deliver it not just to investors but to all stakeholders. In this session, learn tips, best practices, and success stories from building a sustainability story from the ground up.

Catherine Buan, Asana Head of Investor Relations
Larry Lawrence, Intercontinental Exchange Sustainable Finance Data Lead
Moderator: Jen Rogers, Financial Reporter
Watch the full session

Managing Risk in Uncertain Times 
Sponsored and programmed by PwC 

Economic uncertainty and ongoing inflation pose an increasing risk to businesses today. Many leaders cite the risk of cyber security breaches as their main concern. Despite this, business leaders see bright spots and are prioritizing what they can control by doubling down on their growth strategy for this year and beyond. This session will focus on ways companies can manage evolving risks in today’s volatile economy without losing sight of long-term goals. 

Vikas Agarwal, PwC U.S. Risk Products & Technology Leader
Interviewer: Caroline Woods, Business Reporter
Watch the full session

From Original Disruptor to One of the 0.9%

Even in a record-breaking year like 2021, just a tiny, tiny fraction of companies that go public are led by women. Following years on the annual CNBC Disruptor 50 list, 23andMe is now one of the few female-led publicly traded companies, which now has something in common with many disruptors that have come to market before: the challenge of convincing investors to believe in its next act. Co-Founder and CEO Anne Wojcicki has faced challenges before as she overcame regulatory hurdles to build a strong consumer brand and make knowing one’s genetic traits affordable and even cool. She joins us to discuss what’s next and reflect on lessons learned since her company made the very first CNBC Disruptor 50 list in 2013.

Anne Wojcicki, 23andMe Co-Founder & CEO
Interviewer: Julia Boorstin, CNBC Senior Media & Tech Correspondent

Watch the full interview

From Lean In to All In

Jenny Just is one of a very few self-made female billionaires in the United States. In 2020, she founded Poker Power, an organization that teaches women to play poker, and thus improve their strategic thinking and decision-making skills. In this closing session, she’ll explain how Poker Power is empowering women to lead, one hand at a time.

Jenny Just, Poker Power Co-Founder and PEAK6 Co-Founder and Managing Partner
Interviewer: Julia Boorstin, CNBC Senior Media & Tech Correspondent

Watch the full interview